A murine model fed with PE particles showed increased inflammation in small intestines followed by changes in microbiota and increased systemic pro-inflammatory markers [48]
Inositol-containing molecules form part of the phosphatidylinositol signaling system a network that helps cells respond to hormones, including insulin, and regulate downstream metabolic and reproductive processes.15 18 Because these signaling pathways influence insulin sensitivity, glucose handling, ovarian function, and even neurotransmitter activity, researchers have explored inositol supplementation across several clinical contexts.7 Importantly, while mechanistic data are strong, human outcomes vary by population, dose, and form, and many findings remain modest or preliminary.17 The mechanisms most often discussed in the literature fall into a few overlapping categories
Chemosphere 313 , 137582 (2023)
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Distraction of olfactory bulb-medial prefrontal cortex circuit may induce anxiety-like behavior in allergic rhinitis