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There is no pill, supplement, or dietary change that lowers B12. You cannot flush excess B12 by drinking water or eating differently

In addition to decreasing homocysteine levels, which could potentially help reduce the risk of heart disease, some research also indicates that higher vitamin B12 levels may be linked to improved outcomes for those who have suffered from an ischemic stroke and may be associated with a lower risk of coronary artery disease

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This should only be considered under close medical supervision with careful monitoring