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When commencing B12 replacement therapy, it is essential to recognise that pre-existing joint conditions will not resolve with vitamin supplementation alone and may require separate rheumatological assessment and management according to NICE guidelines

doi: 10.1111/j.1365-2044.2004.03712.x

B-12 injections work to protect the nerves, while also reducing the vitamin deficiency that may be causing further damage

W.TitgemeyerE

It exhibits this effect in the presence of the cuprizone toxin, which can cause neuron damage, including demyelination leading to the breakdown of myelin sheaths in the central or peripheral nervous system, without the need to reach the brain