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Experiments conducted on isolated bovine chondrocytes also revealed an apparent upregulation in the production of proteoglycans and collagen in these laboratory settings, fundamental components of the extracellular matrix considered essential for cartilage integrity

Clinical Study 1

In conclusion, this study demonstrated that intra-articular injections of AOD9604 improved cartilage health and functional recovery in a rabbit OA model

Liver steatosis, gut-liver axis, microbiome and environmental factors

methylmalonyl CoA mutase converts methylmalonyl CoA to succinyl CoA, with 5-deoxy adenosyl cobalamin required as a cofactor