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The peptide stimulates the synthesis of chondroitin sulfate and decorin, two essential components of the cartilage matrix

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When p53 was bound to FOXO4, p53 got stuck in the nucleus with the FOXO4 and never made it out the mitochondria where it could start apoptosis

There, we have to assume the dysfunction of the nitrergic pathway (for instance, excision-immediate heavy loss of endothelium cells from the vascular wall results with less NO-production ability (24)), acting differently on the damaged tissue integrity (10, 25)