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The role of GPxs in breast cancer As mentioned above, ROS is closely related to the molecular mechanism of breast cancer progression, and ROS can be directly regulated by GPxs, which eliminate organic peroxides at the expense of GSH [10]

doi:10.1016/j.repbio.2019.07.005

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Although more than 30 bioactive compounds have been isolated, the sesquiterpene lactones found in the leaves of Gymnanthemum amygdalinum have been shown to be the main active compounds responsible for most of the plants therapeutic activities (Luo et al., 2011