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The pharmacokinetic barrier has recently been overcome with the synthesis of the orally active, blood-brain barrierpermeable analog N-hexanoic-tyrosine-isoleucine-(6) aminohexanoic amide (dihexa)

Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

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Possible side effects Compliance with the therapeutic dosage minimizes the risk of unwanted effects of taking the drug

Transurethral Resection of the Prostate (TURP): Considered the gold standard for BPH surgery, TURP involves removing excess prostate tissue through the urethra, providing long-term relief