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GHK-Cu also upregulates VEGF and FGF, supporting its investigation in hair follicle research

Since all compounds present in food possess some functional attributes that may be beneficial for human health, foodome, a concept also known as food-intrinsic metabolome, has been proposed to be introduced as part of the food as medicine (FAM) approach for the treatment of CKD (Mafra et al., 2021)

Oxidative stress mainly damages cartilage homeostasis through excessive accumulation of reactive oxygen species (ROS)

DMF mediates NRF2-dependent and independent mechanisms on TSS pathway CBS activation DMF activates NRF2, the master regulator for the antioxidative stress response, to regulate the expression of proteins involved in iron hemostasis, and GSH synthesis such as HMOX1, NQO1, FTH, FTL, SLC40A1 in a variety of cellular systems 37

Kluwer, Dordrecht, pp 1326 Wu JC, Sun SH, Ke YT, Xie CP, Chen FX (2011) Effects of glutathione on chloroplast membrane fluidity and the glutathione circulation system in young loquat fruits under low temperature stress