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Since retiring from baseball with a World Series ring in 1972 with the Oakland As, Horlen spent many seasons working as a pitching coach, mainly for the San Francisco Giants organization

However, male smokers showed greater improvement in negative symptoms after 12 weeks of treatment, controlling for age, years of education, onset age, and baseline body mass index (BMI)

Med Sci Sports Exerc 1998, 30: 14141418

The authors themselves say, Explaining the sex differences is a challenge. Although the paper speculates that these differences may result from a parental genetic tug-of-war, it does not discuss why smoking during pregnancy should produce traits generally thought of as beneficial in grandchildren