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Pregnant or nursing individuals, those on anticoagulants, and patients with recent surgical wounds require individualized evaluation

Injection vials of 5 mg and 10 mg are also available

Next, EMT is a phenomenon in which epithelial cells acquire mesenchymal cell traits, and it has also been suggested to be associated with cellular infiltration and fibrosis 68

Elevated ROS levels upregulate MMPs and induce the expression of inflammatory factors such as NO synthase, IL-6, IL-1, and TNF-, exacerbating the inflammatory pathology of OA