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Apart from the catalytic or hydroperoxide binding motif, GPxs also harbor the GSH binding motif

It should be noted, however, that according to a study [268], which scrutinized a large panel of cytokines, chemokines, and various immune cell populations, LNPs containing -modified mRNA did not reduce immunogenicity during in vivo experiments in mice

N., Herzigkeit, B., Jurgeleit, R

Sfikakis PP, Iliopoulos A, Elezoglou A et al (2005) Psoriasis induced by anti-tumor necrosis factor therapy: a paradoxical adverse reaction