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Beyond direct effects on serotonin metabolism, polyphenols regulate SERT expression through their anti-inflammatory and antioxidant properties further supporting serotonin homeostasis by mitigating stress-induced increases in SERT activity [211, 212]

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Levels of GFP-tagged stress proteins were monitored using a Nikon TiE2000 confocal laser microscope (lasers: 488 and 408 nm), equipped with a perfect focus system, a controlled temperature (37C) and CO 2 (5%) and an automated stage

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