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It was developed to mimic ghrelin's function in the digestive tract, amplifying peristalsis [13]

EC 1.1.1.49), which catalyses the NAD + - or NADP + -dependent dehydrogenation of -d-glucose 6-phosphate (G6P) to 6-phosphoglucono--lactone

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This broad spectrum of manifestations reflects the complexity of its pathophysiology, which involves a combination of dopaminergic neuron loss, oxidative stress, alpha-synuclein aggregation into Lewy bodies, mitochondrial dysfunction, neuroinflammation, and disruptions in the gut-brain axis 5,6,7,8,9

The envisioned final products are solutions of niclosamide made up in pH buffer and available in 10mL doses in 15 mL nasal and throat spray bottles