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Hepatic global DNA and peroxisome proliferator-activated receptor alpha promoter methylation are altered in peripartal dairy cows fed rumen-protected methionine

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Studies have shown that AMPK has a regulatory function in mitochondria and can reduce ROS levels to prevent OS in oocytes and that the loss of AMPK activity induces a decrease in ATP production and mitochondrial mtDNA copy number

6IL, Supplementary Fig

Its remarkable stability derives primarily from four proline residues at positions 3, 4, 5, and 8, including a distinctive triple-proline (PPP) motif