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Takeaways Methylsulfonylmethane, or MSM, is a compound in animals, humans, and plants

To address the heterogeneity of the included studies, we opted for a structured synthesis based on target populations (e.g., MCI, SCD, mixed samples) and outcome domains (e.g., cognitive, motor, usability)

Immunofluorescence staining and small animal live imaging system PKH26 (Millipore Sigma) was used for pre-labeling particles following the manufacturers instruction

Always pair Glutanex withdaily sunscreen, as UV protection helps maintain an even-looking complexion and supports the results achieved with glutathione