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Consistently, meta-analysis of GWAS studies from Common Metabolic Diseases Knowledge Portal 18 shows that rs1997243-G allele is linked to increased plasma levels of LDL-C, CRP, GGT, ALP, AST, and alanine aminotransferase (ALT) in humans (Supplementary Fig

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It is available in formulations with or without DAC, a modification that can extend its duration of action