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There are reports that Vit B12 & 6, when taken together, caused Monomorphic Acne, many small uniform acne & acne lesions

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However, some individualswhether due to conditions like pernicious anemia, gastrointestinal disorders, or the effects of certain surgeriesmay have trouble absorbing enough B12 from food or oral supplements

B12 Injections and Weight Management While B12 injections are often marketed as a way to boost energy and support weight loss, its important to note that current scientific evidence does not support the use of B12 injections for weight management in individuals with normal B12 levels

Is a Vitamin B12 Shot Right for You