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Exogenous application of GABA in Arabidopsis resulted in an increase in the activity of enzymes associated with nitrogen metabolism, such as nitrate reductase and GOGAT

The pathogenesis of MASLD is multifactorial, involving hepatic lipid accumulation, oxidative stress, inflammation, and dysregulation of the gut-liver axis

When diets lack these nutrients, it can lead to changes in lipid metabolism, increased oxidative stress, and abnormalities in epigenetic processes

238 This complicates mechanistic interpretation and may lead to false-positive or irreproducible findings in high-throughput screening