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As a cofactor of tyrosine hydroxylase, its deficiency leads to lower dopamine production, resulting in increased ADHD symptoms and affecting behavior [121]

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Multiplex quantification of cytokines, hormones and fibrosis markers Concentrations of cytokines, hormones, pro-fibrotic proteins, total protein and collagen were measured in the serum and in BALF samples from patients by multiplex immunoassay analysis (Luminex (R&D) using the Luminex xPONENT software (Thermo Fisher Scientific) and Legendplex (BioLegend)), bicinchoninic acid assay (total protein) or Sircol soluble collagen assay (collagen) according to the manufacturers instructions

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