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Cagrilintide peptide is used in research and clinical development as a long-acting analogue of amylin, a pancreatic hormone involved in satiety, food intake, glucagon regulation, and gastric emptying

IL-6 in inflammation, immunity, and disease

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It is noteworthy that while multiple drug concentrations may be designed in other studies, for our study, minimizing the drug dose while achieving its effect was considered for safety reasons, given that PE is a pregnancy-related disease, and medication use during pregnancy is restricted

As expected, WT mice were unaffected by a low-fat control diet (LFD), a Western diet (WD) or a PUFA-enriched Western diet (PUFA WD) (Fig