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The mechanism of action of BPC 157 is not clear yet

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Many performance-related peptides remain banned in sports and are not FDA-approved for anti-aging purposes

This is because the sustained activation of PI3K-AKT pathway inhibits GSK3, which phosphorylates NRF2 and allows its recognition and ubiquitination by TrCP-CUL1 ubiquitin E3 ligase for degradation

Together, they form a potent defense system against oxidative damage, pigmentation, cellular aging, and environmental stress