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Instead, research points to activity across multiple interconnected systems, including modulation of the nitric oxide (NO) system, upregulation of growth factor expression (notably VEGF, EGF, and FGF pathways), promotion of angiogenesis, and activation of the FAK-paxillin signalling pathway involved in cell migration and tissue organisation
#MUSE #IHC #Immunofluorescence #SignalAmplification #ProteinDetection #Biotech #LifeSciences #Biomarkers #SpatialBiology #Neuroscience To view or add a comment, sign in Exciting to see MUSE signal amplification technology enabling clearer, more sensitive detection in complex tissue
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Failure to clear senescent cells also lead to a pro-tumorigenic microenvironment characterized by chronic inflammation because of the SASP 12,25
