Rotate sites systematically (abdomen at least 2 inches from navel, thighs, upper arms) to avoid lipohypertrophy [8]
PMID: 114 TabeY.HatanakaY.NakashiroM.SekiharaK.YamamotoS.MatsushitaH.et al

Ingredients: Water, Ethylhexyl Methoxycinnamate, Butylene Glycol, Ethylhexyl Salicylate, Octocrylene, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Butyl Methoxydibenzoylmethane, Dipropylene Glycol, Niacinamide (20,000ppm), Squalane, C14-22 Alcohols, 1,2-Hexanediol, Polyglyceryl-2 Stearate, Propanediol, Hydroxyacetophenone, Glyceryl Stearate, Stearyl Alcohol, C12-20 Alkyl Glucoside, Tromethamine, Centella Asiatica Extract (1,510ppm), Carbomer, Melaleuca Alternifolia (Tea Tree) Extract, Hippophae Rhamnoides Fruit Extract, Vitis Vinifera (Grape) Fruit Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Uncaria Sinensis Extract, Glycerin, Adenosine, Disodium EDTA, Oryza Sativa (Rice) Bran Extract, Hydrogenated Phosphatidylcholine, Caprylic/Capric Triglyceride, Sodium Hyaluronate, Glucose, Hydrolyzed Collagen, Sucrose Stearate, Glutathione (10ppm), Cyclodextrin, Cetearyl Alcohol, Caprylyl Glycol, Beta-Glucan, Caprylhydroxamic Acid, Ethylhexylglycerin, Asiatic Acid, Asiaticoside, Madecassic Acid, Madecassoside, Tropolone, Hyaluronic Acid, Potassium Hyaluronate

Due to these mechanical circumstances, the cartilage in these knees is subject to complex stresses that are significantly greater in magnitude than those the healthy green knee would experience
10.1016/j.jtcvs.2005.06.015 J