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systemic side effects are rarely reported in research protocols

Statistical analysis was performed using GraphPad Prism 7.0a, or as reported by the relevant computational tools

In rare cases, some individuals may experience discomfort due to personal constitution or health condition

Signs that scratching has introduced a secondary infection include increasing redness extending outward from the rash border, warmth, swelling, honey-colored crusting, and cloudy or pus-like discharge from blisters