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Signs include fatigue, weakness, and balance problems

[114] This functionality is lost in vitamin B 12 deficiency, and can be measured clinically as an increased serum methylmalonic acid (MMA) concentration

The observed eradication rates ranged from higher than 80% to 40%, depending on patient status, rifabutin dosage, and duration of treatment (Gisbert and Calvet 2012)

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Not a transformation, but a plausible acceleration of tissue repair in a patient whose baseline healing had stalled