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Nature 488 , 665669 (2012)

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This combination downregulates Nrf2 in the cytoplasm while upregulating its nuclear expression, enhancing nuclear translocation and increasing HO-1 mRNA and protein expression

In the present study, rat lenses were cultured in galactose medium to induce opacity formation, and then glutamate was added, which reduced the opacity in the lens cortex at all concentrations of 1 mM, 5 mM, 20 mM, and 40 mM (Fig