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These may impair methylation and cerebral folate transport, with therapeutic implications for folinic acid supplementation

The buildup of misfolded or damaged proteins, such as amyloid- in AD and -synuclein in PD, occurs due to the failure of these pathways, causing cellular stress, inflammation, and neurodegeneration

Transplanting this dysbiotic microbiota into germ-free mice worsened stroke outcomes by driving proinflammatory T-cell responses and promoting lymphocyte migration to the injured brain

100 U/ml Penicillin-Streptomycin, Gibco, 15140-122) at 37C with 5% CO 2