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However, in view of the excellent safety profile of B12, even at high doses, supplementation, ideally as part of a more comprehensive nutritional programme, may still be of value when the clinical picture and/or other factors (e.g

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Additionally, if gastrointestinal adverse effects lead to reduced food intake or changes in dietary vitamin K consumption, warfarin dosing requirements may change

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The injection site should always be cleaned with an alcohol swab and allowed to dry before injecting