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The Cop Operon Is Required for Copper Homeostasis and Contributes to Virulence in Streptococcus pneumoniae

Rodent studies show systemic effects from oral dosing, implying mucosal absorption, but nasal spray is a distinct route with different epithelial barriers

Mean weight reductions were greater with all cagrilintide doses (roughly 6.0% to 10.8%) than with placebo (3.0%), and the top 4.5 mg dose modestly out-performed the active comparator, once-daily liraglutide 3.0 mg (10.8% vs 9.0%)

Compounded medications are not FDA-approved and have not been evaluated by the FDA for safety, effectiveness, or quality

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