In addition, BSO decreased the intensity of Ki67 staining and increased that of 4-HNE staining in tumors with high ACTL6A expression, but this trend was not observed in PDX tumors with low ACTL6A expression (Supplementary Fig 8b)
This review is inherently limited by its predominant focus on preclinical studies conducted in animal models or in vitro systems
Dark spots form when melanin production becomes uneven or excessive in certain areas (a process called hyperpigmentation)
Larger GST-fusion proteins sterically block each other from binding to proximal glutathione ligands
Cardiovasc Diabetol 17:37 Fruzzetti F, Ghiadoni L, Virdis A, De Negri F, Perini D, Bucci F, Giannarelli C, Gadducci A, Taddei S (2016) Adolescents with classical polycystic ovary syndrome have alterations in the surrogate markers of cardiovascular disease but not in the endothelial function