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AS-IV also supports the function of key ion channels (e.g., HCN4) in the heart by enhancing anti-aging protein Klotho expression, reducing arrhythmia likelihood (Qiu et al., 2016)

ETC = the electron transport chain

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doi: 10.1016/j.yexmp.2013.02.002 65 BonillaCMasonTLongLAhaghotuCChenWZhaoAet al