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(2017) Fungal volatile compounds induce production of the secondary metabolite Sodorifen in Serratia plymuthica PRI-2C, Sci
oestradiol (E2) bind ER or ER in mammary epithelial cells, followed by receptor dimerisation, nuclear translocation and direct transcriptional regulation of EREs in promoter regions on target genes that regulate cell proliferation cyclin D1, c-Myc -, survival Bcl-2 or survivin -, angiogenesis VEGF -, EMT Snail, Twist -, metastasis MMPs (185), as non-genomic oestrogen signalling via membrane-localized ER and G proteincoupled oestrogen receptor (GPER) leads to rapid stimulation of PI3K/Akt, MAPK/ERK and Src pathways interacting further impetus to mitogenic and anti-apoptotic effects
In addition, the sample size was small (30 patients), which may not be sufficient to draw comprehensive conclusions
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inhaled during fires and gear off-gassing Combustion Byproducts - released anytime organic and synthetic materials burn PAHs - incomplete combustion
