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Methylene blue neurological benefits include potentially improved cognitive performance and neuroprotection through mechanisms like increasing Nrf2 expression (how much of a protein, called Nuclear factor erythroid 2-related factor 2 (Nrf2), is being made or activated in the cells

May 2010;89(5):447-452

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Therefore, there is an urgent need to develop ultrasensitive, cost-effective, and efficient detection technologies suitable for complex biological matrices to advance the field

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